Applications - Pharmaceutical PAT

LT Industries is now Verum Analytics

New name, new developments, building on 38 years of analytical knowledge.

Process Analytical Technology (PAT) and LT-NIR

The Process Analytical Technology (PAT) initiated by the FDA and EMA seek to improve the efficiency and quality of pharmaceutical production through in-process analysis and control. This involves the design, analysis and control of manufacturing processes through measurement of key process parameters that affect key quality attributes. The goal is to have quality built-in to the manufacturing process, not just tested after (Quality by Design [QbD]). NIR process systems have been widely regarded as a leading technology for the PAT initiative due to their capabilities for rapid, non-destructive analysis of a wide range of chemicals and materials in liquid, solid and slurry forms. LT-NIR has the tools necessary to meet your PAT project goals.

Process Measurement Solutions

Get real-time analysis of:

Mixing and BlendingEnd Product IdentificationFermentation Bioreactors
API drying and coatingRaw Material AnalysisCell culture
GranulationPolymorphic Formsand more…

LT-NIR Process systems are designed to be user-friendly, easy to integrate, and extremely cost effective. With up to 20 measurement points per analyzer, sterilizable CIP/SIP probes, and communication software for Modbus, 4-20mA and other protocols, designing a PAT solution with a high rate of return is within reach. LT Industries also provides commissioning, model development, and training onsite. Continuing product support is always available following installation–the systems can be accessed and troubleshooted remotely by LT’s team of experts.

Additional Pharmaceutical Measurements

LT-NIR can also handle final product quality tests and incoming material validation. Measure dosage in tablets, uniformity, actives and excipients. Identify grades, sources, and counterfeits in seconds for raw materials and final products. IsoPharm Benchtop instruments can be used by operators of any skill level. Analysis is done with the push of a button and qualitative or quantitative results are displayed on screen in accordance with your measurement requirements.


Applications – Listing
Acetonitrile and AlcoholACN and Alcohol – request more information
Adhesive GelatinGelatin, Pectin, and NaCMC – request more information
Ampicillin/AmpicyllinPotency & Moisture – request more information
AmoxicillinPotency, Trihydrate, & Moisture – request more information
Antibiotics FermentationActive Ingredient, Fat, and Nitrate – request more information
Bacterial Growth – Algae% Sodium Acetate in Algae Growth – request more information
BloodGlucose & Glucose in Saline – request more information
Cough Drop% Menthol – request more information
Cough SyrupAcetaminophen – request more information
Dosage% Dosage of Olanzapine – request more information
Ecoli FermentationAcetate, Optical Density, Product Titer (Protein)  – request more information
FermentationGlucose, Glutamin, & Antigesic Mass – request more information
Fermentation of EcoliDry Cell Weight, OD, Ethanol (EtOH)  – request more information
Fermentation of Mammalian CellsGlucose, Lactate, Glutamate, and more  – request more information
GemfribrozilDosage of Assay – request more information
Herbal MedicinesGlycyrrhizin, Baicaline & Paeoniflorine – request more information
Isradipine% Active (dosage) – request more information
Lypholized Products% Moisture – request more information
Medical PatchesNCO – request more information
MixtureMeasurement of batch mixture – request more information
MouthwashGlycerine & Alcohol – request more information
Pharmaceutical PowdersWater Content – request more information
PharmaceuticalsEnalapril Maleate – request more information
PharmaceuticalsDosage Forms, Optical Isomers, Polymorphism, & Particle Size – request more information
Polymorphic PhaseDetermination of molecular phase – request more information
Raw Material IDDiscrimination between raw materials – request more information
Setraline HCLDetermination of Polymorphic phase – request more information
SuspensionDosage (%Doxicillin) – request more information
Tablet – Didanosine%Active – request more information
TetracyclineCalculated Assay, REL CPD #1 – request more information